Bowtrol Cause of irritable bowel syndrome
As discussed previously, irritable bowel syndrome is believed to
be due to the abnormal function (dysfunction) of the muscles of
the organs of the gastrointestinal tract or the nerves
controlling the organs. The nervous control of the
gastrointestinal tract, however, is complex. A system of nerves
runs the entire length of the gastrointestinal tract from the
esophagus to the anus in the muscular walls of the organs. These
nerves communicate with other nerves that travel to and from the
spinal cord. Nerves within the spinal cord, in turn, travel to
and from the brain.
(The gastrointestinal tract is exceeded in
the numbers of nerves it contains only by the spinal cord and
brain.) Thus, the abnormal function of the nervous system in IBS
may occur in a gastrointestinal muscular organ, the spinal cord,
or the brain.
The nervous system that controls the gastrointestinal organs, as
with most other organs, contains both sensory and motor nerves.
The sensory nerves continuously sense what is happening within
the organ and relay this information to nerves in the organ's
wall. From there, information can be relayed to the spinal cord
and brain. The information is received and processed in the
organ's wall, the spinal cord, or the brain. Then, based on this
sensory input and the way the input is processed, commands
(responses) are sent to the organ over the motor nerves. Two of
the most common motor responses in the intestine are contraction
or relaxation of the muscle of the organ and secretion of fluid
and/or mucus into the organ.
As already mentioned, abnormal function of the nerves of the
gastrointestinal organs, at least theoretically, might occur in
the organ, spinal cord, or brain. Moreover, the abnormalities
might occur in the sensory nerves, the motor nerves, or at
processing centers in the intestine, spinal cord, or brain. Some
researchers argue that the cause of functional diseases is
abnormalities in the function of the sensory nerves. For
example, normal activities, such as stretching of the small
intestine by food, may give rise to abnormal sensory signals
that are sent to the spinal cord and brain, where they are
perceived as pain.
Other researchers argue that the cause of functional diseases is
abnormalities in the function of the motor nerves. For example,
abnormal commands through the motor nerves might produce a
painful spasm (contraction) of the muscles. Still others argue
that abnormally functioning processing centers are responsible
for functional diseases because they misinterpret normal
sensations or send abnormal commands to the organ. In fact, some
functional diseases may be due to sensory dysfunction, motor
dysfunction, or both sensory and motor dysfunction. Still others
may be due to abnormalities within the processing centers One
area that is receiving a great deal of scientific attention is
the potential role of gas produced by intestinal bacteria in
patients with IBS. Studies have demonstrated that patients with
IBS produce larger amounts of gas than individuals without IBS,
and the gas may be retained longer in the small intestine. Among
patients with IBS, abdominal size increases over the day,
reaching a maximum in the evening and returning to baseline by
the following morning. In individuals without IBS, there is no
increase in abdominal size during the day.
There has been a great deal of controversy over the role that
poor digestion and/or absorption of dietary sugars may play in
aggravating the symptoms of IBS. Poor digestion of lactose, the
sugar in milk, is very common as is poor absorption of fructose,
a sweetener found in many processed foods. Poor digestion or
absorption of these sugars could aggravate the symptoms of IBS
since unabsorbed sugars often cause increased formation of gas.
Although these abnormalities in production and transport of gas
could give rise to some of the symptoms of IBS, much more work
will need to be done before the role of intestinal gas in IBS is
clear.
Dietary fat in healthy individuals causes food as well as gas to
move more slowly through the stomach and small intestine. Some
patients with IBS may even respond to dietary fat in an
exaggerated fashion with greater slowing. Thus, dietary fat
could--and probably does--aggravate the symptoms of IBS.
For more information visit:
Bowcontrol
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